Research activities

Optimizing the Effectiveness and Cost-Effectiveness of Public Health Interventions

Optimizing the effectiveness and cost-effectiveness of public health interventions is crucial for maximizing health outcomes within limited resources. We employ optimization algorithms to achieve specific objectives, such as minimizing infections or fatalities during an outbreak, identifying intervention priorities and optimal coverage, and utilizing cost-effectiveness analysis to measure the effectiveness of interventions.

Papers and Research Reports

Cost effectiveness of fractional doses of COVID-19 vaccine boosters in India

Du Z, Wang L, Bai Y, Feng S, Ramachandran S, Lim WW, Lau EHY, Malani A, Cowling BJ

Med (2023)

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Modeling comparative cost-effectiveness of SARS-CoV-2 vaccine dose fractionation in India

Du Z, Wang L, Pandey A, Lim WW, Chinazzi M, Piontti APY, Lau EHY, Wu P, Malani A, Cobey S, Cowling BJ

Nature Medicine (2022)

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Comparative cost-effectiveness of SARS-CoV-2 testing strategies in the USA: a modelling study

Du Z, Pandey A, Bai Y, Fitzpatrick MC, Chinazzi M, Pastore Y Piontti A, Lachmann M, Vespignani A, Cowling BJ, Galvani AP, Meyers LA

The Lancet. Public Health (2021)

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Multimodeling approach to evaluating the efficacy of layering pharmaceutical and nonpharmaceutical interventions for influenza pandemics

Prasad PV, Steele MK, Reed C, Meyers LA, Du Z, Pasco R, Alfaro-Murillo JA, Lewis B, Venkatramanan S, Schlitt J, Chen J, Orr M, Wilson ML, Eubank S, Wang L, Chinazzi M, Pastore Y Piontti A, Davis JT, Halloran ME, Longini I, Vespignani A, Pei S, Galanti M, Kandula S, Shaman J, Haw DJ, Arinaminpathy N, Biggerstaff M

Proceedings of the National Academy of Sciences of the United States of America (2023)

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Cost-effective proactive testing strategies during COVID-19 mass vaccination: A modelling study

Du Z, Wang L, Bai Y, Wang X, Pandey A, Fitzpatrick MC, Chinazzi M, Pastore Y Piontti A, Hupert N, Lachmann M, Vespignani A, Galvani AP, Cowling BJ, Meyers LA

Lancet Regional Health. Americas (2022)

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Optimizing COVID-19 surveillance using historical electronic health records of influenza infections

Du Z, Bai Y, Wang L, Herrera-Diestra JL, Yuan Z, Guo R, Cowling BJ, Meyers LA, Holme P

PNAS Nexus (2022)

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