Research activities

Modeling Within-Host and Between-Host Dynamics in Infectious Disease Transmission

Using agent-based methods, we model and optimize healthcare interventions, such as vaccination and drugs, in a framework that combines within-host and between-host dynamics. We address several fundamental questions about (a) modeling pathogen and immune responses (including drugs) in infected individuals to understand what determines disease severity and infectiousness and (b) modeling pathogen transmission at the population level.

Papers and Research Reports

Within-host dynamics of SARS-CoV-2 infection: A systematic review and meta-analysis

Du Z, Wang S, Bai Y, Gao C, Lau EHY, Cowling BJ

Transboundary and Emerging Diseases (2022)

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Modeling mitigation of influenza epidemics by baloxavir

Du Z, Nugent C, Galvani AP, Krug RM, Meyers LA

Nature Communications (2020)

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Cost-effective proactive testing strategies during COVID-19 mass vaccination: A modelling study

Du Z, Wang L, Bai Y, Wang X, Pandey A, Fitzpatrick MC, Chinazzi M, Pastore Y Piontti A, Hupert N, Lachmann M, Vespignani A, Galvani AP, Cowling BJ, Meyers LA

Lancet Regional Health. Americas (2022)

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